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Expert Pearls

Fibromyalgia - coenzyme q10 - 48643

Coenzyme Q10 300 mg/d (soft gel capsules) in three divided doses with meals. [Mitochondrion, 2011 April 7; [Epub ahead of print]. 48643 (5/2011)] Summary Interview PubMed

Fibromyalgia - d-ribose - 41201 / 42747

D-ribose at 5 gms t.i.d. with or without meals for approximately 3 weeks (loading dose) then 5 gm b.i.d. for up to six weeks (can stop if no benefit). [Pharmacotherapy, 2004;24(11):1646-1648. 41201/42747 (02/2005)] Summary Interview

Fibromyalgia - d-ribose - 44986 / 45599

D-ribose at 5 gms t.i.d. with or without meals for approximately 3 weeks (loading dose) then 5 gm b.i.d. for up to six weeks (can stop if no benefit). [J Altern Complement Med, 2006 Nov;12(9):857-62. 44986/45599 (4/2007)] Summary Interview PubMed

Fibromyalgia - gluten free diet - 50583

A gluten-free diet improved digestive complaints in patients with combined fibromyalgia and irritable bowel syndrome found to have celiac disease. There was a significant prevalence (6.7%) of celiac disease in subjects with fibromyalgia and irritable bowel syndrome. [Arthritis Res Ther. 2013;15(6):R201. 50583 (12/2014)] Interview PubMed

Fibromyalgia - vitamin B1 - 50480

Vitamin B1 (thiamine HCL) orally between 600-1800 mg/d in 2-3 divided doses (before 5: p.m.) with meals starting at 600 mg daily and tapered up every 3 days by 300 mg until energy is increased and fibromyalgia symptoms are reduced at the highest dose without side effects. Minimal and reversible side effects are mild tachycardia, anxiety and sleep disturbances. IM thiamine at 100 mg/ml given at 1 ml weekly is equivalent to 1800-2000 mg per day orally, while 100 mg IM of thiamine every 4 days is equivalent to 4000 mg orally each day. Thiamine is kept up for life at a level of symptom reduction, energy enhancement and without side effects. [BMJ Case Rep. 2013 May 20;2013. 50480 (12/2014)] Interview PubMed

Fibromyalgia - vitamin d - 49825

Vitamin D supplementation of 1200 IU or 2400 IU to achieve a serum level between 32-48 ng/ml significantly reduced pain in fibromyalgia patients. [Pain, 2014 Feb;155(2):261-8. 49825 (4/2014)] Summary Interview PubMed
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