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Expert Pearls

Immune Function - antioxidant, green tea, leukocytes - 51037

Green tea extract 100 mg three times daily for 14 days showed a significant increase in the activation of leukocytes and a significant increase in the total antioxidant status. [J Complement Integr Med. 2015 Aug 8. 51037 (12/2015)] Interview PubMed

Immune Function - Beta-carotene

Beta-carotene 15 mg/d enhance cell-mediated immune response. [J Lab Clin Med, 1997;129:309-317. 26885 (1997)] Summary Interview

Immune Function - docosahexaenoic acid, dha - 48916

DHA 400 mg/day (each softgel capsule containing 100 mg DHA) taken from the twelfth week of gestation and continued until the end of the fourth post-partum month in breast-feeding women improved cytotoxicity and reduced pro-inflammatory mediators in infants. [Mediators Inflamm. 2011;2011:493925 48916 (12/2011)] Summary Interview PubMed

Immune Function - Linoleic acid rich diets

Linoleic acid rich diets (maize-based diets) deficient in other polyunsaturated fatty acids and riboflavin resulted in high tissue production of prostaglandin E2, which in turn caused inhibition of the proliferation and cytokine production of Th1 cells, mediators of cellular immunity, increasing the risk to tuberculosis, measles, hepatoma, secondary infection in HIV and kwashiorkor. [Postgraduate Med J, March 1999;75(881):129-132. 32852 (1999)] Summary Interview

Immune Function - Spirulina

Spirulina (blue-green algae) 4g (20 tablets) at a time, twice a day (one in the morning, and another in the afternoon), regardless of food intake reduced cholesterol, IL-6 and increased IL-2. [Ann Nutr Metab, 2008;52(4):322-328. 46595 (11/2008)] Summary Interview

Immune Function - Vitamin B6

Vitamin B6 50-100 mg I.M. per day enhanced immune function in critically ill patients. [Eur J Clin Nutr, 2006 Oct;60(10):1207-13. Epub 2006 May 3. 44727/45422 (2/2007)] Summary Interview

Immune Function - Vitamin C

Vitamin C 1 gm b.i.d. (with breakfast and dinner) prevented monocyte dysfunction in smokers; normal monocyte function stimulates collateral arteriogenesis. [Arterioscler Thromb Vasc Biol, 2007; 27(1): 120-6. 45084 (4/2007)] Summary Interview

Immune Function - vitamin d - 49744

Vitamin D3 (cholecalciferol) supplementation at 140,000 IU/month for 3 months in a single dose dissolved in vegetable oil after a12 hour fast lead to a significant increase in the numbers of peripheral Tregs in vivo with no side effects. Regulatory T cells (Tregs) mainly suppress proinflammatory responses by other immune cells thus preventing exaggerated immune or autoimmune responses. [Eur J Nutr, 2013 Sept 3; [Epub ahead of print]. 49744 (1/2014)] Summary Interview PubMed

Immune Function - Yogurt

Yogurt with probiotics and without 100 - 200 ml/d (100 ml of probiotic yogurt = 109 L. delbrueckii, 2 x 1010 S. thermophilus and 3.7 x 1010 of L. casei DN 114 001; 100 ml conventional yogurt = 6.4 x 109 L. delbrueckii and 3.9 x 109 S. thermophilus). [Ann Nutr Metab, 2006;50(3):282-9. Epub 2006 Feb 23. 44407/45009 (10/2006)] Summary Interview

Immune Function - Zinc gluconate

Zinc gluconate (45 mg elemental zinc) daily in a single or divided dose away from meals reduced infections, tumor necrosis factor alpha, oxidative stress markers. [Am J Clin Nutr, 2007 Mar;85(3):837-44. 45161/45884 (8/2007)] Summary Interview
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