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Expert Pearls

Mood Disorders - Exercise

Exercise - as little as 10 minutes of brisk walking can reduce psychological tension and enhance feelings of energy. Moderate intensity that elevates breathing and a degree of sweating occurs, is generally sufficient. More exercise, in general, seems to be better than just a little. People who exercised for 2 to 7 hours a week were psychologically "healthier" than people who did little or no exercise at all. Exercisers who engaged in 8 to 10 hours of activity a week were even "healthier." People should do whatever form of exercise they enjoy for as long as they can manage. Something is better than no exercise. [J Psychosomatic Med, 1996;40(2):123-141. 24395 (1997)] Summary Interview

Mood Disorders - Omega-3 fatty acids

Omega-3 fatty acids (EPA>DHA) 1 gm/d. [Am J Psychiatry, 2006 Jun;163(6): 96978. 44481/45041 (8/2006)] Summary Interview

Mood Disorders - Thiamine

Thiamine 50 mg/d. [Psychopharmacology, 1997;129:66-71. 26997 (1997)] Summary Interview

Mood Disorders - vitamin c - 49724

Vitamin C at 500 mg two times daily with or without meals in acutely hospitalized patients reduced mood disturbance and distress while 5000 IU of vitamin D had no effect. Vitamin C levels normalized while vitamin D levels remained deficient. Vitamin D may need a much larger loading dose, possibly 300,000 IU, to normalize levels in the acute care setting. [Am J Clin Nutr, 2013 July 24; [Epub ahead of print]. 49724 (9/2013)] Summary Interview PubMed

Mood Disorders - vitamin-mineral supplements - 49627

Vitamin and mineral supplementation had positive benefits on perception of stress, mild psychiatric symptoms and general mood in non-clinical, healthy adult populations in a meta-analysis of 8 double-blind randomized controlled trials. [Psychosom Med, 2013 Feb;75(2):144-53. 49627 (8/2013)] Summary Interview PubMed
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