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Expert Pearls

Pancreatitis (acute) - prebiotic - 45426

Prebiotic fiber at 15 grams of fructooligosaccharide per day fed through nasojejunal feeding tubes reduced length of hospital stay and infection rate in subjects with acute pancreatitis. [World J Gastroenterol, 2007;13(19): 2733-7. 45426 (5/2009)] Summary Interview PubMed

Pancreatitis (acute) - selenium - 22503

Selenium 1000 mcg (from sodium selenite) in 3 to 6 liters of intravenous fluids with carbohydrates and electrolytes (no calcium) on the first day; second day 500 mcg. Analgesics via enemas 3 times per day. Efficacy of treatment can be seen by the rapid lowering of malondialdehyde in the blood and the normalization of calcium values. After motility of the colon returns give orally; vitamin E 400 I.U., beta-carotene 15 mg, vitamin C 500 mg two times a day, methionine 400 mg, zinc 50 mg, magnesium 600 mg, vitamin B6 20 mg, selenium 200 mcg (selenomethionine), N-acetylcysteine 600 mg (3 200 mg tablets) and folic acid 500 mcg. [Med. Klin., 1995;90:Suppl. I:36-41. 22503 (1995)] Summary Interview PubMed

Pancreatitis (chronic) - antioxidant therapy - 31928

Antioxidant therapy using selenium, vitamins C and E, and glutathione inducers such as N-acetylcysteine have potential benefit. [Digestion 1998;59 (Suppl. 4):13-24. 31928 (1999)] Summary Interview PubMed

Pancreatitis (chronic) - antioxidants - 32819

Antioxidants - patients had significantly lower plasma concentrations of selenium, vitamin A, vitamin E, beta-carotene, xanthine, beta-cryptoxanthine and lycopene than control subjects and patients with recurrent acute pancreatitis. [Am J Gastroenterol 1999;94:2135-2140. 32819 (1999)] Summary Interview PubMed

Pancreatitis (chronic) - antioxidants/oxidant stress - 22503

Antioxidants/oxidant stress low plasma concentrations of glutathione, selenium, vitamins C and E and methionine, and high concentrations of TBARS in all forms of pancreatitis. [Med. Klin., 1995;90:Suppl. I:36-41. 22503 (1995)] Summary Interview PubMed

Pancreatitis (chronic) - glutathione - 31928

Glutathione - low levels in pancreatitis. [Digestion 1998;59(Suppl. 4):13-24. 31928 (1999)] Summary Interview PubMed

Pancreatitis (chronic) - xenobiotic exposure - 31928

Xenobiotic exposure. [Digestion 1998;59(Suppl. 4):13-24. 31928 (1999)] Summary Interview PubMed
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