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Expert Pearls

Polycystic Ovarian Syndrome (PCOS) - chromium picolinate - 44692

Chromium picolinate 500 mcg b.i.d. with meals. [Fertil Steril, 2006; 86(1):243-6. 44692 (1/2007)] Summary Interview

Polycystic Ovarian Syndrome (PCOS) - folic acid, metformin - 47613

Folic acid at 400 mcg/d with metformin at 1700 mg/d reduced the slight increase in homocysteine levels with metformin alone and maintained the positive effect that metformin has on endothelial function in PCOS subjects. [Diabetes Care, 2009 Nov 23; [Epub ahead of print]. 47613 (01/2010)] Summary Interview PubMed

Polycystic Ovarian Syndrome (PCOS) - spearmint tea - 45091

Spearmint tea - A cup spearmint tea (steeped with M. Spicata) twice a day for 5 days during the follicular phase of the menstrual cycle, showed after 5 days a significant decrease in free testosterone levels. [Phytother Res, 2007 Feb 20; [Epub ahead of print]. 45091 (5/2007)] Summary

Polycystic Ovarian Syndrome - folic acid, inositol - 50771

Inositol as 4 grams of myo-inositol/day plus 400 mcg of folic acid/day or 1 gram of D-chiro-inositol/day plus 400 mcg of folic acid/day orally improved ovarian function and metabolism. Myo-inositol showed the most marked effect on the metabolic profile, whereas D-chiro-inositol reduced hyperandrogenism better. [Gynecol Endocrinol. 2014 Mar;30(3):205-8. 50771 (5/2105)] Interview PubMed

Polycystic Ovarian Syndrome - n-acetylcysteine - 50904

N-acetylcysteine (NAC) 1200-1800 mg/day divided into 2-3 doses after the meals in women with PCOS resulted in a higher odds of ovulation, getting pregnant and having a live birth as compared to placebo. NAC therapy is well tolerated with good patient compliance. [Obstet Gynecol Int. 2015;2015:817849. 50904 (9/2015)] Interview PubMed
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