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Expert Pearls

Renal Failure (hemodialysis) - Carnitine

Carnitine (L-) I.V. at 20 mg/kg/d over 2-3 minutes after end of every hemodialysis treatment session. [Indian J Med Sci, 200; 60(4):143-53. 44507 (10/2006)] Summary Interview

Renal Failure (hemodialysis) - Carnitine - 2

Carnitine (L-) 3 gm/d. [Cardiovas Drugs Ther, 1999;13:537-546. 35944 (1999)] Summary Interview

Renal Failure (hemodialysis) - Hyperhomocysteinemia, folic acid, vitamin B-6, vitamin B12

Hyperhomocysteinemia treated with folic acid 1 mg/d, vitamin B-6 10 mg/d and vitamin B12 12 ug/d; an additional 30% non-fasting homocysteine reduction occurs in non-fasting hemodialysis patients with the addition of folic acid 15 mg/d, vitamin B-6 100 mg/d and vitamin B12 1 mg/d. [Kidney International, 1996;49:147-152. 24342 (1996)] Summary Interview

Renal Failure/Insufficiency (chronic) - Coenzyme Q10

Coenzyme Q10 (QGel™) 30 mg, 2 caps 3 x daily. [J Nutr Environ Med, 2000;10:281-288. 36843 (2001)] Summary

Renal Failure/Insufficiency (chronic) - Protein

Protein intake 0.6 gm/d/kg body weight (lowering the amount of protein intake reduces the risk of end stage renal disease, i.e. reaching the need for dialysis, by 30% in most diabetic and non-diabetic patients; should not be done in those excreting more than 10 gms/d). [Ann Intern Med, April 1, 1996;124(7):627-632. 24530 (1996)] Summary Interview

Renal Failure/Insufficiency (chronic) - Protein - 2

Protein (30% soy protein, 35% textured soy protein and 35% animal protein) .8 mg/kg/d. [Diabetes Care, 2008; 31(4): 648-54 in diabetics. 46326 (8/2008)] Summary Interview

Renal Failure/Insufficiency (chronic) - Vitamin E

Vitamin E 300 to 800 IU/d. [Redox Report, 1997;3(5/6):259-261. 31002 (1999)] Summary Interview

Renal Function - Magnesium

Magnesium deficiency (lower [Mg2+]) is associated with a faster renal function deterioration rate in DMII patients. [Clin Nephrology, July 2005;63(6):429-436. 43396 (8/2005)] Summary Interview

Renal Function - N-acetylcysteine

N-acetylcysteine 150 mg/kg and then 15 mg/kg/hr from a continuous I.V. infusion inhibited the adverse effects of E. coli endotoxin on renal function. [Crit Care Med, 2007; 35(8):1869-75. 46020 (7/2008)] Summary Interview
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