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Expert Pearls

Stroke - 1,25 dihydroxyvitamin D

1,25 dihydroxyvitamin D low predictive. [Nutr Metab Cardiovasc Dis. 2005 Jun;15(3):188-97. 43761 (10/2005)] Summary Interview

Stroke - amino acids, branched-chain - 48363

Amino acid mixture (Aminotrofic®) composed of 50% branched-chain amino acids given in two daily doses via a nasogastric tube in the ICU. [ Neurocrit Care, 2010, Oct 23; [Epub ahead of print]. 48363 (1/2011)] Summary Interview PubMed

Stroke - Antioxidants

Antioxidants - vitamin E 800 IU (727 mg) and vitamin C 500 mg within 12 hours post-infarct after acute stroke enhanced antioxidant capacity, mitigated oxidative damage and reduced tissue inflammation. [Eur J Clin Nutr, 2005 Dec;59(12):1367-73. 43890/44353 (2/2006)] Summary Interview

Stroke - Aspirin

Aspirin 325 mg/d and vitamin E 400 I.U./d reduced risk of ischemic stroke 25% more than ASA alone. [Am J Clin Nutr, 1995;62(suppl):1381S-1384S. 23791 (1996)] Summary Interview

Stroke - b vitamin- 49769

B vitamin supplementation reduced stroke events from reducing homocysteine levels. Folic acid 0.8 mg, vitamin B12 400 mcg and B6 40 mg was a common dose. [Neurology, 2013 Sept 18; [Epub ahead of print]. 49769 (12/2013)] Summary Interview PubMed

Stroke - Caffeine

Caffeine intake daily may increase deaths from stroke 17 to 24 percent. [The Lancet, 1997;349:279-281. 27049 (1997)] Summary Interview

Stroke - coffee - 47016

Coffee does not increase stroke risk; intakes of 2 or more cups per day versus less than 1 cup per month may reduce risk. [Circulation, 2009 Feb 16; [Epub ahead of print]. 47016 (5/2009)] Summary Interview PubMed

Stroke - Diet

Diet rich in potassium, magnesium and fiber is protective against stroke mortality in men. [Br J Nutr, 2000;84:5-17. 35798 (2000)] Summary

Stroke - Diet - 2

Diet rich in fruits and vegetables (at least 5 serving per day), legumes, fish, grains and cereals. [Br J Nutr, 2000;84:5-17. 35798 (2000)] Summary

Stroke - Exercise

Exercise (regular) reduces risk. [Br J Nutr, 2000;84:5-17. 35798 (2000)] Summary

Stroke - Fish

Fish consumption in women two to four times per week had a 48% decrease in risk of thrombotic stroke; fish 5+ times/week had a 70% decreased risk of thrombotic stroke. Women who ate fish two to four times per week had a 27% decrease in total and a 37% decrease in ischemic stroke, while those who ate fish 5+ times per week had a 52% decrease in total stroke and a 62% decrease in ischemic stroke. Omega-3 fatty acid intake, 87% of which was from seafood/fish sources, women in the highest quintile had a significant 28% decrease in total stroke, with nonsignificant reductions in risk of ischemic stroke (29%), and thrombotic stroke (33%). No increased risk of hemorrhagic stroke was observed. [JAMA, 2001;285: 304-312. 33726 (2001)] Interview

Stroke - Fish - 2

Fish two to four times per week reduced the risk of thrombotic stroke 48%; fish 5+ times/week reduced risk 70% . [JAMA, 2001;285:304-312. 33726 (2001)] Interview

Stroke - Fish - 3

Fish two to four times per week reduce risk of total stroke 27% and ischemic stroke 37% in women; fish 5+ times per week reduced risk of total stroke 52% and reduce the risk of ischemic stroke 62% in women. [Eur J Clin Nutr, 2005 Dec;59(12):1367-73. 43890/44353 (2/2006)] Summary Interview

Stroke - Fruit and vegetable

Fruit and vegetable consumption lower risk. [Br J Nutr, 2000;84:5-17. 35798 (2000)] Summary

Stroke - green tea - 50050

Green tea consumption in ascending order of intake 1 to 5 or more cups per day is associated with a reduction in functional disability (cognitive function, depression, psychological distress, stroke) and healthy life expectancy, in a dose dependent fashion. [Am J Clin Nutr. 2012 March;95(3):732-739. 50050 (5/2012)] Interview PubMed

Stroke - Homocysteine

Homocysteine is a risk factor. [Br J Nutr, 2000;84:5-17. 35798 (2000)] Summary

Stroke - Homocysteinemia/homocystinuria

Homocysteinemia/homocystinuria is a risk factor. [NEJM, February 2, 1995;332 (5):328-329. 21740 (1996)] Summary Interview

Stroke - Iron

Iron low in serum is predictive. [Nutr Metab Cardiovasc Dis. 2005 Jun;15(3): 188-97. 43761 (10/2005)] Summary Interview

Stroke - Isoflavone

Isoflavone 80 mg/day in a single dose with or without food. [Eur Heart J, 2008 Sept 23; [Epub ahead of print]. 46714 (12/2008) Summary

Stroke - mediterranean diet - 48965

Diet - Mediterranean-style diet, defined as a diet with a high intake of fruits, vegetables, monounsaturated fat, fish, whole grains, legumes, and nuts, moderate alcohol consumption, and a low intake of red meat, saturated fat, and refined grains, was associated with a decreased risk of having a vascular event. [Am J Clin Nutr, 2011 Dec;94(6):1458-64 48965 (01/2012)] Summary Interview PubMed

Stroke - soft drinks - 50161

Calorie containing soft drinks including caloric sweeteners such as sucrose, or high-fructose corn syrup (HFCS), cola-type beverages, flavored juices and non-100% fruit increased stroke, especially ischemic stroke, by 20% and 80% respectively in Japanese women (highest intake group compared to the lowest) between 40 and 59 years of age but not in men. [Am J Clin Nutr, 2012 Dec;96(6):1390-7. 50161 (12/2012)] Interview PubMed

Stroke - Tocotrienols

Tocotrienols 200 mg b.i.d. with meals may be protective. [Mol Aspects Med. 2007 Oct-Dec;28(5-6):692-728. Epub 2007 Mar 27. 46221 (6/2008)] Summary Interview

Stroke - vegetarian diet - 49219

Vegetarians have lower : all cause mortality; ischemic heart disease (IHD) ; mortality from circulatory diseases; mortality from cerebrovascular disease; significantly lower cancer incidence than nonvegetarians. Vegetarians have reduced cardiovascular risk factors compared with omnivores including: decreased body mass index; waist to hip ratio; blood pressure; plasma total cholesterol (TC); triglycerides; LDL-C levels; serum lipoprotein(a); plasma factor VII activity; the ratio of TC/HDL-C, LDL-C/HDL-C and TAG/HDL-C, and serum ferritin levels. [Ann Nutr Metab, 2012 Jun 1;60(4):233-240. 49219 (7/2012)] Summary Interview PubMed
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