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Expert Pearls

Asthma (exercise-induced) - Antioxidants

Antioxidants possibly. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Beta-carotene

Beta-carotene (algae -Dunaliella) 64 mg/d. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Caffeine

Caffeine. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Gluten-free diet

Gluten-free diet kept subjects symptom-free. [J Allergy Clin Immunol May 1999;103(5/Part I):912-917. 38431/32251 (1999)] Summary Interview PubMed

Asthma (exercise-induced) - LYC-O-MATO™

LYC-O-MATO™ 30 mg/d. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Omega-3 fatty acids

Omega-3 fatty acids EPA 3.2 gm/d and DHA 2.2 mg/d. [Am J Respir Crit Care Med, 2003;168:1181-1189. 42680 (02/2005)] Summary Interview PubMed

Asthma (exercise-induced) - Omega-3 fatty acids - 2

Omega-3 fatty acids (fish and fish oil) increase intake. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Omega-6 fatty acids

Omega-6 fatty acids reduction. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Omega-6:Omega-3 fatty acid

Omega-6:Omega-3 fatty acid ratio of 2.3:1. [Am J Respir Crit Care Med, 2003;168:1181-1189. 42680 (02/2005)] Summary Interview PubMed

Asthma (exercise-induced) - Salt reduction

Salt reduction < 2400 mg/d. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma (exercise-induced) - Vitamin C

Vitamin C 500 mg t.i.d. with meals. [Respir Med, 2007 Aug;101(8):1770-8. 45198 (3/2008)] Summary Interview PubMed

Asthma (exercise-induced) - Vitamin C - 2

Vitamin C increase. [Sports Med, 2003;33(9):671-681. 40979 (2003)] Summary Interview PubMed

Asthma - acupuncture - 49222

Acupuncture performed 3 x per week for 5 weeks with needles being twisted approximately 360° evenly at the rate of 60 times/min for 20 seconds, manipulated every 10 minutes, and withdrawn after 30 minutes including the acupoint selection GV 14, BL12 and BL13. [Clin Rev Allergy Immunol, 2012 Jun 3; [Epub ahead of print]. 49222 (7/2012)] Summary Interview PubMed

Asthma - Antibiotic

Antibiotic use in the first year of life increases asthma incidence possibly by altering gut flora or exposure to infections. Clin Exp Allergy 1999 29 766-771 32449/33002 1999 Summary Interview PubMed

Asthma - Antioxidants

Antioxidants - coenzyme Q10 (120 mg/day Q-Gel®), alpha-tocopherol (400 mg/day) and vitamin C (250 mg/day) reduced steroid need. Biofactors 2005 25 1-4 235-40 44573 10/2006 Summary Interview PubMed

Asthma - Antioxidants, fish oil, reduce salt

Antioxidants, fish oil, reduce salt. Eur J Clin Nutr Dec 2005 59 12 1335-46 43952/44350 3/2006 Summary Interview PubMed

Asthma - carnitine - 50213

Carnitine at 1050 mg in a single daily dose of 3 capsules each morning 30 minutes before meals for 6 months.

[J Allergy (Cairo). 2012;2012:509730 50213 (5/2013)] Interview PubMed

Asthma - Causes/foods

Causes of increase: processed foods; less fresh foods; increased omega-6:omega-3 ratio; more fast foods containing high levels of salt, sugar and omega-6 fatty acids and low levels of omega-3 fatty acids and antioxidants. Allergy 1995 50 935-938 24196/24296 1996 Summary Interview PubMed

Asthma - developed countries

Incidence highest in developed countries. Eur Respir J 1999 29 766-771 32449/33002 1999 Summary Interview PubMed

Asthma - Diet/antioxidants

Diet low in antioxidants increases asthma symptoms and reduces pulmonary function. Free Radic Res 2008 42 1 94-102 46151 5/2008 Summary Interview PubMed

Asthma - Eicosapentaenoic acid/docosahexaenoic acid

Eicosapentaenoic acid (EPA) 3.2 g/d and docosahexaenoic acid (DHA) 2.0 g/d in divided doses with meals (exercise-induced asthma). Chest Jan 2006 129 1 39-49 44022/46306 11/2006 Summary Interview PubMed

Asthma - Food allergy by elimination diet

Food allergy by elimination diet; most frequently offending foods in descending order were fruit, grains, proteins and vegetables. South African Allergy Society Congress and the South African Pulmonary Society Congress 1999 1-10 32726 1999 Summary Interview

Asthma - Food allergy by elimination diet - 2

Food allergy by elimination diet; most frequently offending foods in descending order were fruit, grains, proteins and vegetables. South African Family Practice July 1990 355 25182 Summary Interview

Asthma - food concentrate, fruit, vegetable - 49449

Food concentrates in a combination pill form equivalent to 4 servings of fruit and vegetables, 1 serving of fish (1065-1775 mg = of fish oil = 1-1 ½ servings of deep sea fish per day), and 1 serving of yogurt a day (= 2x 109 colony forming units of Lactobacillus ) taken immediately after breakfast in asthmatic children significantly reduced medication use and improved pulmonary function. [Br J Nutr, 2012 Dec 5:1-11. 49449 (1/2013)] Summary Interview PubMed

Asthma - green lipped mussel - 49683

Green lipped mussel product PCSO-524™ in 8 capsules per day containing approximately 72 mg EPA and 48 mg DHA daily (1 capsule contains 50 mg n-3 PUFAs and 100 mg olive oil) showed reduction in bronchodilator use and symptoms, airway inflammation and the severity of bronchoconstriction following a hyperpnea airway challenge.

[Respir Med, 2013 Aug;107(8):1152-63. 49683 (10/2013)] Summary Interview PubMed

Asthma - Herbal medications

Herbal medications (ex. Ma Huang -Ephedra). J Asthma 1999 36 1 1-65 32662 1999 Summary Interview PubMed

Asthma - Lycopene

Lycopene 45 mg/d (from tomato juice or lycopene 15 mg per capsule (Lyc-o-Mato®) taken three times per day with a slice of white bread spread with olive oil margarine). Free Radic Res 2008 42 1 94-102 46151 5/2008 Summary Interview PubMed

Asthma - Magnesium

Magnesium (MgSO4) nebulized; varying dose regimens:1152 mg (384 mg every 20 minutes x 3 doses); 453 mg (151 mg every 30 minutes x 3 doses); 2.5 mL 3.18% solution (x 1 dose); 380 mg (95 mg every 20 minutes x 4 doses); 135 mg (x 1 dose); and 225 mg (x 1 dose). [Chest, July 2005;128(1):337-344. 43487 (8/2005)] Chest July 2005 128 1 337-344 43487 8/2005 Summary

Asthma - Magnesium (MgSO4) I.V.

Magnesium (MgSO4) I.V. 2 gm over 20 minutes in adults; children 50-100 mg/kg or up to 2 gm over 20 minutes in children. J Allergy Clin Immunol Jan 2006 117 1 53-8 33192/44695 4/2006 Summary Interview PubMed

Asthma - Magnesium - 2

Magnesium (MgSO4)) nebulized 3 ml (3.2% solution, 95 mg of magnesium diluted in normal saline) given every 15 minutes for 1 hour in addition to a single 100 gm I.V. bolus of hydrocortisone. Eur Respira J 1998 12 341-344 31547 1999 Summary Interview PubMed

Asthma - Magnesium glycinate

Magnesium glycinate 300 mg/d in a single dose away from meals (children). Eur J Clin Nutr Jan 2007 61 1 54-60 44396/ 45746 7/2007 Summary Interview PubMed

Asthma - Maternal elimination diet

Maternal elimination diet benefits nursing infants. South African Allergy Society Congress and the South African Pulmonary Society Congress 1999 1-10 32726 1999 Summary Interview

Asthma - Multivitamin/mineral

Multivitamin/mineral intake in exclusively formula-fed infants had a 70% increased risk for developing food allergies by 3 years of age if taken before 6 months of age as compared to exclusively formula fed infants who did not. Pediatrics July 2004 114 1 27-32 41857/41843 2004 Summary Interview PubMed

Asthma - Omega-3:omega-6 fatty acids

Omega-3:omega-6 fatty acids should be increased (more fish, alpha-linolenic acid and monounsaturated fatty acids and reduce corn, sunflower and safflower oils). [Australian New Zealand Journal of Medicine, 1994; 24:727. 21648 (1995)] Australian New Zealand Journal of Medicine 1994 24 727 21648 1995 Summary Interview PubMed

Asthma - Oxidant stress

Oxidant stress from decreased glutathione production increases asthma incidence. J Am Coll Nutr 1995 14 4 317-324 23054 1996 Summary Interview PubMed

Asthma - Pycnogenol®

Pycnogenol® 1 mg/lb along with elimination of processed-fast food, sugary beverages, dairy products and increasing water intake. [J Asthma, 2004;41(8):825-832. 42953 (4/2005)] Summary Interview PubMed

Asthma - Risk factors

Risk factors include: excess iron and lead; reduced vitamins C, E and selenium; G6PD deficiency; anything that reduces the endogenous production of glutathione. [J Am Coll Nutr, 1995;14(4):317-324. 23054 (1996)] Summary Interview PubMed

Asthma - Selenium

Selenium (sodium selenite)100 mcg/d for 3 months increased serum selenium levels, GSH-Px activity and reduced asthma symptoms. [J Am Coll Nutr, 1995;14(4):317-324. 23054 (1996)] Summary Interview PubMed

Asthma - Trans fatty acids

Trans fatty acids increase risk. [The Lancet, June 12, 1999;353:2040-2041. 32340 (1999)] Summary Interview PubMed

Asthma - vitamin c - 50321

Vitamin C 1-5 grams per day decreased the occurrence of asthma attacks or bronchial reactivity in those who had upper respiratory infections. Individual therapeutic trials of vitamin C are encouraged as soon as cold symptoms start with doses up to, or above 6-8 grams per day. No one knows the most clinically beneficial dose of vitamin C. Vitamin C is cheap and safe. [Allergy Asthma Clin Immunol. 2013 Nov 26;9(1):46. 50321 (5/2014)] Interview PubMed

Asthma - vitamin d - 49236

Vitamin D insufficiency below 30 ng/ml was associated with higher risk of having had at least one severe asthma exacerbation in the prior year and children with asthma who had vitamin D insufficiency had a higher risk of allergy and a lower FEV1/FVC, a measure of lung function. [J Respir Crit Care Med, 2012 May 31; [Epub ahead of print]. 49236 (8/2012)] Summary Interview PubMed
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