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Expert Pearls

Hepatoxicity - Cirrhosis

Cirrhosis - vitamin A intake about 400 x 106 IU/d; non-cirrhotic portal hypertension - 150 x 106 IU/d; 20 x 106 IU/d the lowest dose observed to induced liver damage. [Am J Med, April 1995;98(4) 424. 22235 (1995)] Summary Interview

Hepatoxicity - Lipoic acid

Lipoic acid (thioctic acid) I.V. reversed hepatic necrosis from acute Amanita poisoning. [New Mexico Supplement To The Western Journal of Medline, May 1995:162(5);2. 29872, 33497, 33817, 34827/23950 (1996)] Summary Interview
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