Age Related Macular Degeneration (AMD) - endothelial dysfunction, lifestyle - 51070
Age-related macular degeneration (AMD) is a result of lifestyle factors that result in disordered functioning of endothelium (ED) in the vessels supplying the affected ocular structures with blood (choroidalneovascularization [CNV]). AMD is a local manifestation of systemic vascular disease. Treatment includes lifestyle modification by AMD-patients: (1) smoking cessation; (2) reduction of body weight (slimming); (3) regular, appropriate physical activity; (4) prescribing a low glycemic, phytochemically rich diet which includes: (a) flavonoids, (b) polyphenols (c) omega-3 long-chain polyunsaturated fatty acids (docosahexaenoic acid and eicosapentaenoic acid); (d) carotenoids (lutein and zeaxanthin); (e) management of dietary glycemic index (GI); (5) caloric restriction (CR); (6) elimination/discontinuance of the stressful lifestyle.
Orv Hetil. 2015 Jul 12;156(28):1128-32. 51070